Thermodynamic measures of cancer: Gibbs free energy and entropy of protein–protein interactions
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چکیده
منابع مشابه
Thermodynamic measures of cancer: Gibbs free energy and entropy of protein-protein interactions.
Thermodynamics is an important driving factor for chemical processes and for life. Earlier work has shown that each cancer has its own molecular signaling network that supports its life cycle and that different cancers have different thermodynamic entropies characterizing their signaling networks. The respective thermodynamic entropies correlate with 5-year survival for each cancer. We now show...
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The nonadditive thermodynamic formalism is a generalization of the classical thermodynamic formalism, in which the topological pressure of a single function φ is replaced by the topological pressure of a sequence of functions Φ = (φn)n. The theory also includes a variational principle for the topological pressure, although with restrictive assumptions on Φ. Our main objective is to provide a ne...
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پس ازفروپاشی شوروی،رشد منابع نفت و گاز، آسیای میانه و قفقاز را در یک بازی ژئوپلتیکی انرژی قرار داده است. با در نظر گرفتن این منابع هیدروکربنی، این منطقه به یک میدانجنگ و رقابت تجاری برای بازی های ژئوپلتیکی قدرت های بزرگ جهانی تبدیل شده است. روسیه منطقه را به عنوان حیات خلوت خود تلقی نموده و علاقمند به حفظ حضورش می باشد تا همانند گذشته گاز طبیعی را به وسیله خط لوله مرکزی دریافت و به عنوان یک واس...
15 صفحه اولGibbs Free Energy of Protein-Protein Interactions reflects tumor stage
The sequential changes occurring with cancer progression are now being harnessed with therapeutic intent. Yet, there is no understanding of the chemical thermodynamics of proteomic changes associated with cancer progression/ cancer stage. This manuscript reveals a strong correlation of a chemical thermodynamic measure (known as Gibbs free energy) of protein-protein interaction networks for seve...
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ژورنال
عنوان ژورنال: Journal of Biological Physics
سال: 2016
ISSN: 0092-0606,1573-0689
DOI: 10.1007/s10867-016-9410-y